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Performance of a MethyLight assay for methylated SFRP2 DNA detection in colorectal cancer tissue and serum

Background: Colorectal cancer is one of the five most common cancers in China, and its incidence is steadily increasing...

Performance of a Novel Blood-Based Early Colorectal Cancer Screening Assay in Remaining Serum after the Blood Biochemical Test

Background: Combination of multiple biomarkers was an effective strategy to improve sensitivity in cancer diagnosis and screening...

A novel plasma based early colorectal cancer screening assay base on methylated SDC2 and SFRP2

Methylated SFRP2 was previously reported as a non-invasive biomarker for colorectal cancer (CRC) detection with a relatively low sensitivity for early stage CRC. The purpose of this study...

Multiplex Methylated DNA Testing in Plasma with High Sensitivity and Specificity for Colorectal Cancer Screening

Colorectal cancer (CRC) is the most common malignancy of gastrointestinal tract and among the three most common cancer types worldwide...

Feasibility of Plasma-Methylated SFRP2 for Early Detection of Gastric Cancer

Gastric cancer (GC) is fifth most frequently diagnosed cancer and second leading cause of cancer in China. More than 80% of GC are diagnosed at an advanced stage...

Performance comparison between plasma and stool methylated SEPT9 tests for detecting colorectal cancer

Colorectal cancer (CRC) is the most common type of malignancies of the gastrointestinal tract worldwide. Plasma methylated SEPT9 test has been used clinically...

Aberrant DNA Methylation of SEPT9 and SDC2 in Stool Specimens as an Integrated Biomarker for Colorectal Cancer Early Detection

Colorectal cancer (CRC) has become the second leading cause of new cancer cases and the fifth of cancer deaths in China, and early detection is the most effective...

Methylated SFRP2 and SDC2 in stool specimens for Colorectal Cancer early detection: A cost-effective strategy for Chinese population

The aim of this study was to evaluate the feasibility of combination of methylated SFRP2 and methylated SDC2 (SpecColon test) in stool specimens for colorectal...

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